This open access book explores the socio-economic challenges and recovery efforts in Cambodia, Laos, Vietnam, and Myanmar during the COVID-19 pandemic. It focuses on the pandemic’s wide-ranging impacts, particularly on individuals, households, and small and medium-sized enterprises across key sectors such as agriculture, garment manufacturing, and tourism. The analysis incorporates cross-cutting themes, including gender disparities and social protection, highlighting the uneven effects on different demographics. The book also discusses the policy responses adopted by these countries to mitigate socio-economic challenges. It examines the mechanisms employed during policy implementation, identifying key lessons for managing crises in the region. The book aims for a diverse audience, including students, researchers, policymakers, and development practitioners. Offering evidence-based insights, this volume is an important resource for understanding crisis management and policy development in the context of developing countries.