This important and timely Research Handbook explores recent scholarship on industry innovation and demonstrates that the key to a sustainable future is a successful transition to a circular bioeconomy. Global case studies are analysed to illustrate the motivations, factors, ecosystems, and barriers surrounding circular bioeconomies. The authors discuss and evaluate innovations from diverse industries, including agri-food, marine biorefinery, insect farming, and waste management. They also shed light on firm-level innovation to better understand possible solutions for a successful transition into a circular bioeconomy, advancing current thinking in the field. The empirical and theoretical work presented offers new directions for future research into a circular bioeconomy. This Research Handbook is a vital reference for researchers of innovation, circular bioeconomies, climate change and the Sustainable Development Goals. It is also of great interest to industry practitioners across agriculture and manufacturing, who can use the insights presented to guide their own sustainable decision-making.